
Innovation, Reliability & Customer-Focused
Liquid Heating and Cooling
Solutions
About
AIS (Applied Integrated Systems, Inc.) specializes in the manufacturing of inline, high-purity, chemical heaters and chillers; recirculating chillers and heaters; thermoelectric heating and cooling systems; DI water heaters and chillers; and high-purity heat exchangers. Our advanced solutions are designed for precise process temperature control, offering exceptional reliability, cost efficiency, and short manufacturing cycle times to meet the demands of diverse industrial applications.

Our Products
Engineered thermal solutions for precision, purity, and reliability.
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Applied Integrated Systems designs and manufactures high-performance heating and cooling solutions for demanding industrial and semiconductor applications. Our products are built to deliver precise temperature control, chemical compatibility, and long-term reliability in mission-critical environments.
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High-Purity Inline Heaters - Designed for ultra-pure chemical and DI water processes
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Recirculating & High-Purity Chillers - Stable, efficient temperature control for process tools and systems
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High-Purity Heat Exchangers - Optimized for corrosive chemistries and contamination-sensitive applications
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Custom Thermal Systems & Assemblies - Engineered solutions tailored to your specific process requirements
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​​Each system is developed with a focus on performance, safety, and seamless integration into your process.
Our heating and cooling solutions are used by leading OEMs, semiconductor fabs, and advanced manufacturing companies...












Company logos are trademarks of their respective owners and are used solely to indicate a business relationship. Use of logos does not imply endorsement.

Industries We Serve
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Semiconductor Manufacturing: Heating process chemicals used in wafer fabrication, etching, cleaning, and stripping.
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Pharmaceuticals: Maintaining precise temperatures during drug formulation, sterile steam generation, media & nutrient heating, fermentation, and API (Active Pharmaceutical Ingredient) synthesis.
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Chemical Processing: Managing exothermic reactions, ensuring consistent product quality, chemical synthesis, polymerization, and catalytic reactions.
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Biotechnology: Controlling temperatures in bioreactors, incubators, fermentation tanks, and water baths – essential for enzyme reactions, DNA amplification, and protein studies.
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Food and Beverage: Regulating temperatures during production, pasteurization, sterilization, and packaging processes.
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Solar Energy: Ensuring optimal temperature control for the production and testing of solar panels, as well as managing thermal systems in solar energy storage.
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Aerospace & Defense: Providing temperature control solutions for manufacturing and testing high-performance materials, as well as cooling and heating applications in military equipment.
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Automotive Manufacturing: Supporting temperature regulation in parts manufacturing, battery testing, and cooling systems for electric vehicles (EVs).








